Search Result

Results for "

β-Sitosterol-d<sub>7</sub> (Mixture of Diastereomers)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (10) 11β-HSD (3) 5 alpha Reductase (5) 5-HT Receptor (59) AAK1 (1) Acetolactate Synthase (ALS) (1) Acyltransferase (1) ADAMTS (1) ADC Cytotoxin (10) Adenosine Receptor (5) Adrenergic Receptor (63) AIM2 (1) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (2) Aminopeptidase (1) AMPK (5) Amyloid-β (5) Anaplastic lymphoma kinase (ALK) (7) Androgen Receptor (13) Angiotensin Receptor (17) Angiotensin-converting Enzyme (ACE) (8) Antibiotic (150) Antifolate (7) Apoptosis (202) Aryl Hydrocarbon Receptor (5) ATM/ATR (1) ATP Citrate Lyase (2) Autophagy (228) Bacterial (216) Bcl-2 Family (6) Bcr-Abl (6) BCRP (3) Beta-lactamase (2) Beta-secretase (1) Biochemical Assay Reagents (28) Btk (6) c-Fms (1) c-Kit (13) c-Met/HGFR (4) Calcineurin (2) Calcium Channel (45) Cannabinoid Receptor (7) Carbonic Anhydrase (4) Casein Kinase (1) Caspase (8) CaSR (2) Cathepsin (2) CCR (2) CD73 (2) CDK (15) CFTR (5) CGRP Receptor (1) Chloride Channel (2) Cholinesterase (ChE) (17) CMV (1) Complement System (5) COMT (4) COX (61) CRISPR/Cas9 (2) CTLA-4 (1) Cuproptosis (1) CXCR (1) Cytochrome P450 (28) Deubiquitinase (1) Dihydrofolate reductase (DHFR) (2) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (9) DNA Alkylator/Crosslinker (8) DNA/RNA Synthesis (66) Dopamine Receptor (39) Drug Metabolite (47) Drug-Linker Conjugates for ADC (3) DYRK (3) E1/E2/E3 Enzyme (2) EBI2/GPR183 (1) EGFR (18) Endogenous Metabolite (735) Endothelin Receptor (3) Enolase (1) Enterovirus (2) Epigenetic Reader Domain (4) ERK (7) Estrogen Receptor/ERR (39) Factor Xa (2) FAK (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (36) FGFR (9) FKBP (5) Flavivirus (5) FLT3 (7) Fluorescent Dye (20) Fungal (53) FXR (4) G protein-coupled Bile Acid Receptor 1 (2) G-quadruplex (1) GABA Receptor (22) Gap Junction Protein (2) GCGR (1) Glucocorticoid Receptor (23) Glucosidase (2) Glucosylceramide Synthase (GCS) (2) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (1) GnRH Receptor (2) GPR35 (1) GPR88 (1) GSK-3 (3) HBV (8) HCV (13) HCV Protease (3) HDAC (18) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (4) Histamine Receptor (22) Histone Acetyltransferase (5) Histone Demethylase (5) Histone Methyltransferase (5) HIV (48) HIV Integrase (7) HIV Protease (7) HMG-CoA Reductase (HMGCR) (11) HSP (5) HSV (13) IAP (1) IGF-1R (3) iGluR (16) IKK (3) Imidazoline Receptor (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (31) Insulin Receptor (1) Integrin (2) Interleukin Related (6) Isotope-Labeled Compounds (1532) JAK (7) JNK (1) Kallikrein (1) Keap1-Nrf2 (11) Ketohexokinase (2) Kinesin (1) Lactate Dehydrogenase (1) Leukotriene Receptor (8) Ligands for E3 Ligase (4) Ligands for Target Protein for PROTAC (1) Liposome (20) Lipoxygenase (1) LPL Receptor (7) LXR (1) mAChR (32) MDM-2/p53 (3) MEK (3) Melanocortin Receptor (1) Melatonin Receptor (8) mGluR (8) MicroRNA (1) Microtubule/Tubulin (20) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (5) Mitophagy (36) MMP (6) Molecular Glues (7) Monoamine Oxidase (9) Monoamine Transporter (1) mTOR (4) Myosin (4) Na+/K+ ATPase (4) nAChR (13) NAMPT (1) Neprilysin (6) Neurokinin Receptor (5) NF-κB (29) NO Synthase (18) NOD-like Receptor (NLR) (4) Notch (7) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (57) Opioid Receptor (2) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (9) P2X Receptor (1) P2Y Receptor (6) p38 MAPK (4) PAK (6) Parasite (62) PARP (3) PD-1/PD-L1 (3) PDGFR (14) PDI (1) PGE synthase (1) Phosphatase (7) Phosphodiesterase (PDE) (18) Phospholipase (5) PI3K (2) PKA (2) PKC (5) Potassium Channel (18) PPAR (18) Progesterone Receptor (20) Prostaglandin Receptor (21) PROTAC Linkers (2) PROTACs (7) Proteasome (1) Proton Pump (14) PTEN (1) RABV (1) Raf (6) RAR/RXR (5) Ras (3) Reactive Oxygen Species (41) Renin (2) RET (5) Reverse Transcriptase (6) ROCK (1) ROR (2) ROS Kinase (4) RSV (6) SARS-CoV (39) Ser/Thr Protease (5) Serotonin Transporter (22) SGLT (4) Sigma Receptor (1) Sirtuin (5) Small Interfering RNA (siRNA) (1) Sodium Channel (26) Src (2) STAT (5) STING (5) Syk (1) TAM Receptor (3) Telomerase (1) TGF-beta/Smad (4) TGF-β Receptor (2) Thrombin (7) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (3) TMV (2) TNF Receptor (8) Toll-like Receptor (TLR) (5) Topoisomerase (17) Transketolase (1) Trk Receptor (3) TRP Channel (13) Tryptophan Hydroxylase (1) Tyrosinase (4) VD/VDR (20) VEGFR (19) Virus Protease (13) Wnt (1) Xanthine Oxidase (2) β-catenin (1) γ-secretase (1)
By Research Areas:	Cancer (701) Cardiovascular Disease (182) Endocrinology (156) Infection (373) Inflammation/Immunology (304) Metabolic Disease (333) Neurological Disease (342)
Click Chemistry:	Azide (2) Alkynes (14)

2794

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

159

Recombinant Proteins

2417

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Nuclear Factor of activated T Cells (NFAT) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132382S

β-Sitosterol-d7 (mixture of diasteromers)	Isotope-Labeled Compounds	Others
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].

HY-134670S

*α-Hydroxy Metoprolol-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].

HY-132676S

Ramiprilat-d5 (Mixture of Diastereomers)

Isotope-Labeled Compounds Others

Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

*Ramiprilat-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)** DS5565-¹³C<sub>2sub>,d<sub>1sub> (Mixture of Diastereomers)	Isotope-Labeled Compounds	Others
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-132379S

*Hydroxy Pioglitazone-d5 (M-IV) (Mixture* of-diastereomers)**	Isotope-Labeled Compounds	Others
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**	Endogenous Metabolite Isotope-Labeled Compounds	Others
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-D1249

*Calcein (mixture* of isomers)**	Fluorescent Dye	Others
Calcein mixture of isomers is a calcium-dependent fluorescent molecule. Calcein mixture of isomers can be used to study bone metabolism (in vivo) and to stain depressed areas (in vitro). Calcein mixture of isomers can also be used for fluorometry and EDTA titration of calcium.

HY-14620A

*Farnesene (mixture* of isomers)**	Others	Others
Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-131152

*Leucinostatin (mixture* of A&B)**	Antibiotic	Infection Inflammation/Immunology
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics .

HY-W250128

*Dodecenylsuccinic anhydride (mixture* of isomers)** DDSA (Mixture of isomers)	Biochemical Assay Reagents	Others
2-Dodecen-1-Ylsuccinic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Dodecenylsuccinic anhydride (mixture of isomers) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N6013

*Aloin(mixture* of A&B)**	MMP Bacterial Fungal	Infection Inflammation/Immunology Cancer
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-132637S

*Chlorfenvinphos-d10(Mixture* of cis-trans isomers)**	Isotope-Labeled Compounds	Others
Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-W018772

*D-Ribose(mixture* of isomers)** 3 Publications Verification	Endogenous Metabolite	Inflammation/Immunology Cancer
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-W018772S15

*D-Ribose(mixture* of isomers)-13C5**	Endogenous Metabolite
D-Ribose(mixture of isomers)- ¹³C₅ isomers)- ¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

HY-107327S

Carazolol-d7

(±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>
Adrenergic Receptor Others

Carazolol-d₇ is the deuterium labeled Carazolol[1].

Carazolol-d7 (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>	Adrenergic Receptor	Others
Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7 Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>	Isotope-Labeled Compounds Apoptosis Autophagy Bacterial	Inflammation/Immunology Cancer
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-66005S2

Acetaminophen-d7 Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>	COX Endogenous Metabolite Histone Acetyltransferase	Inflammation/Immunology
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7 Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7 Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>	Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds	Others
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-D0711S2

Indocyanine green-d7 Foxgreen-d<sub>7sub>; IC Green-d<sub>7sub>; Cardiogreen-d<sub>7sub>	Isotope-Labeled Compounds Fluorescent Dye	Others
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-10792A

*Eplivanserin (mixture)* SR-46349 (Mixture)	Serotonin Transporter 5-HT Receptor	Neurological Disease
Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT_2A receptor antagonist, extracted from patent WO 2005/002578 A1 .

HY-12057S1

Vemurafenib-d7 PLX4032-d<sub>7sub>; RG7204-d<sub>7sub>; RO5185426-d<sub>7sub>	Isotope-Labeled Compounds Raf Autophagy	Cancer
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

HY-Y0376S

DMPA-d7

Bis-MPA-d<sub>7sub>; Dimethylolpropionic acid-d<sub>7sub>; Nikkamer PA-d<sub>7sub>
Isotope-Labeled Compounds Others

DMPA-d₇ is the deuterium labeled DMPA[1].

DMPA-d7 Bis-MPA-d<sub>7sub>; Dimethylolpropionic acid-d<sub>7sub>; Nikkamer PA-d<sub>7sub>	Isotope-Labeled Compounds	Others
DMPA-d₇ is the deuterium labeled DMPA[1].

HY-113679

Ceramides Mixture 1 Publications Verification	Telomerase	Metabolic Disease Endocrinology
Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .

HY-41700S3

D-Alanine-d7 (R)-Alanine-d<sub>7sub>; Ba 2776-d<sub>7sub>; D-α-Alanine-d<sub>7sub>	Endogenous Metabolite
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-135328S

Norverapamil-d7 (±)-Norverapamil-d<sub>7sub>; D591-d<sub>7sub>	Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-17025S

Rifabutin-d7 Ansamycin-d<sub>7sub>; LM-427-d<sub>7sub>	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7 (±)-Mevalonolactone-d<sub>7sub>; Mevalolactone-d<sub>7sub>	Endogenous Metabolite	Metabolic Disease
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

HY-B0679S

Lubiprostone-d7 RU-0211-d<sub>7sub>; SPI-0211-d<sub>7sub>	Chloride Channel	Metabolic Disease
Lubiprostone-d₇ (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

HY-50898S1

Lapatinib-d7 dihydrochloride GW572016-dd<sub>7sub> dihydrochloride; GW2016-dd<sub>7sub> dihydrochloride	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-12296S

Navtemadlin-d7 AMG 232-d<sub>7sub>; KRT-232-d<sub>7sub>	Isotope-Labeled Compounds MDM-2/p53 E1/E2/E3 Enzyme	Cancer
Navtemadlin-d₇ is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

HY-13720AS

Pergolide-d7 mesylate Pergolide methanesulfonate-d<sub>7sub>; LY127809-d<sub>7sub>	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium Chenodeoxycholylglycine-d<sub>7sub> (sodium); Sodium glycochenodeoxycholate-d<sub>7sub>	Endogenous Metabolite Apoptosis	Cancer
Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-12785S1

Albendazole sulfoxide-d7 Ricobendazole-d<sub>7sub>; Albendazole oxide-d<sub>7sub>	Isotope-Labeled Compounds Parasite	Infection
Albendazole sulfoxide-d₇ is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

HY-14268S1

Febuxostat-d7 TEI 6720-d<sub>7sub>; TMX 67-d<sub>7sub>	Isotope-Labeled Compounds Xanthine Oxidase	Metabolic Disease Cancer
Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

HY-B1674S4

(±)-Leucine-d7 DL-Leucine-d<sub>7sub>; (RS)-Leucine-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite Bacterial
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

HY-N0650S11

L-Serine-d7 (-)-Serine-d<sub>7sub>; (S)-Serine-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N7745S

Glucosylsphingosine-d7

Glucopsychosine-d<sub>7sub>; Lyso-Gb1-d<sub>7sub>
Isotope-Labeled Compounds Others

Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

Glucosylsphingosine-d7 Glucopsychosine-d<sub>7sub>; Lyso-Gb1-d<sub>7sub>	Isotope-Labeled Compounds	Others
Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-135853S

Molnupiravir-d7 EIDD-2801-d<sub>7sub>; MK-4482-d<sub>7sub>	SARS-CoV Influenza Virus	Inflammation/Immunology
Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

HY-14275S1

Verapamil-d7 (±)-Verapamil-d<sub>7sub>; CP-16533-1-d<sub>7sub>	Isotope-Labeled Compounds Calcium Channel P-glycoprotein Cytochrome P450	Metabolic Disease Cancer
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-101047S

D-erythro-Sphingosine-d7 Erythrosphingosine-d<sub>7sub>; erythro-C18-Sphingosine-d<sub>7sub>; trans-4-Sphingenine-d<sub>7sub>	PKC Phosphatase Endogenous Metabolite	Cancer
D-erythro-Sphingosine-d₇ is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].

HY-B0763S2

Ibudilast-d7-1 KC-404-d<sub>7sub>-1; AV-411-d<sub>7sub>-1; MN-166-d<sub>7sub>-1	Phosphodiesterase (PDE)
Ibudilast-d₇-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].

HY-Y1772S

1-Iodo-4-methylbenzene-d7 p-Iodotoluene-d<sub>7sub>; p-Methyliodobenzene-d<sub>7sub>; p-Tolyl iodide-d<sub>7sub>	Isotope-Labeled Compounds	Others
1-Iodo-4-methylbenzene-d₇ is the deuterium labeled 1-Iodo-4-methylbenzene[1].

HY-14291S1

Vildagliptin-d7 LAF237-d<sub>7sub>; NVP-LAF 237-d<sub>7sub>	Isotope-Labeled Compounds Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-B1178S2

(Rac)-Cotinine-d7

(±)-Cotinine-d<sub>7sub>; (Rac)-NIH-10498-d<sub>7sub>
Isotope-Labeled Compounds Endogenous Metabolite Others

(Rac)-Cotinine-d₇ is deuterium labeled Cotinine.

HY-N2026S

Propylparaben-d7 Propyl parahydroxybenzoate-d<sub>7sub>; Propyl 4-hydroxybenzoate-d<sub>7sub>	Isotope-Labeled Compounds	Others
Propylparaben-d₇ (Propyl parahydroxybenzoate-d₇)is the deuterium labeledPropylparaben(HY-N2026) . Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6013

*Aloin(mixture* of A&B)**	Infection Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Inflammation/Immunology Disease Research Fields	MMP Bacterial Fungal
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-W018772

*D-Ribose(mixture* of isomers)** 3 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-139637

(±)-Silybin Silibinin (Mixture of Silybin A and Silybin B)	Structural Classification Flavanonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Others
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-131152

*Leucinostatin (mixture* of A&B)**	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Inflammation/Immunology Disease Research Fields Other Antibiotics	Antibiotic
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N8549A

5-Dihydrocortisone	Structural Classification Classification of Application Fields Cardiacglycosides Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
5-Dihydrocortisone is a 5-Dihydrocortisone with mixture of isomers. 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver

HY-B0504S

Creatinine-d3 NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-113434B

5-HETE (±)-5-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-N7265

Epi-galantamine	Alkaloids other families Source classification Plants	Cholinesterase (ChE)
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC₅₀ of 45.7 μM .

HY-W794998

Cedarwood terpenes	Structural Classification Other Monoterpenes Cedrus deodara (Roxburgh) G. Don Pinaceae Terpenoids Source classification Plants	Others
Cedarwood terpenes is a natural terpene mixture that can be extracted from cedar wood .

HY-N2078

Yamogenin Neodiosgenin	other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields Steroids	LXR
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-N7084

Methyl dihydrojasmonate	Classification of Application Fields Oleaceae Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields jasminum grandiflorum	Others
Methyl dihydrojasmonate is a fragrance ingredient with a jasmine-like odor, used in many fragrance mixtures .

HY-N0683A

rel-α-Vitamin E rel-D-α-Tocopherol	Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Others
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture .

HY-10448A

Capsaicinoid (65%Capsaicin)	Structural Classification Monophenols Capsicum annuum L. Neurological Disease Classification of Application Fields Source classification Phenols Solanaceae Plants Inflammation/Immunology Disease Research Fields	TRP Channel Autophagy Apoptosis Endogenous Metabolite
Capsaicinoid (65%Capsaicin) is a mixture of Capsaicin and Dihydrocapsaicin. Capsaicinoid is an capsaicin receptor (TRPV1) agonist .

HY-B0399A

DL-Carnitine (±)-Carnitin	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Mitochondrial Metabolism
DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.

HY-B2236

DL-Lysine (±)-2,6-Diaminocaproic acid	Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Others
DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins .

HY-114158A

Pronase E (Activity ≥ 4000 U/mg) 4 Publications Verification Pronase (Activity ≥ 4000 U/mg)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Pronase E (Activity ≥ 4000 U/mg) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .

HY-114158

Pronase E (Activity ≥ 7000 U/g) 5+ Cited Publications Pronase (Activity ≥ 7000 U/g)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Pronase E (Activity ≥ 7000 U/g) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .

HY-120109

13-HODE methyl ester	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
13-HODE methyl ester, a racemic mixture of 13(R)-HODE methyl ester and 13(S)-HODE methyl ester, is a 15-lipoxygenase metabolite of Linoleic acid .

HY-N2543

Damascenone (E/Z)-Damascenone	Natural Products Microorganisms Classification of Application Fields Source classification Rosaceae Plants Disease Research Fields Inflammation/Immunology Rosa rugosa Thunb.	NF-κB Endogenous Metabolite
Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity . Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.

HY-N4301

Monensin B	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA .

HY-N10129

Uvaretin	Infection Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Dihydrochalcones Disease Research Fields	Bacterial
A mixture of uvaretin and isouvaretin (HY-N10130) exhibits significant antibacterial activity against B. subtilis (EC₅₀ 8.7 μM) and S. epidermidis (IC₅₀ 7.9 μM).

HY-N10130

Isouvaretin	Infection Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Dihydrochalcones Disease Research Fields	Bacterial
A mixture of uvaretin (HY-N10129) and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC₅₀ 8.7 μM) and S. epidermidis (IC₅₀ 7.9 μM).

HY-N5056

DL-Goitrin	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases cruciferous vegetables Plants Brassicaceae Disease Research Fields	Influenza Virus
DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of cruciferous vegetables .

HY-116663

(±)20-HDHA (±)20-HDoHE	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate .

HY-N8425

Octacosanoic acid Montanic acid	Classification of Application Fields Croton caudatus Geisel. Croton. Ketones, Aldehydes, Acids Source classification Metabolic Disease Euphorbiaceae Plants Disease Research Fields	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-B2134

Casanthranol	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Others
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions .

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-N7497

Protoescigenin	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-N6706

Enniatin complex	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Other Antibiotics	Bacterial Acyltransferase Apoptosis
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-120435

Tyrothricin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Fungal Influenza Virus Antibiotic
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .

HY-W355141

Isopulegol	Structural Classification Natural Products Classification of Application Fields Source classification Essence, Fragrance Myrtaceae Cosmetic Research Plants Disease Research Fields Cancer Eucalyptus citriodora Hook. f.	Others
Isopulegol is one of the main components of ECO (Eucalyptus citriodora oil). ECO has antibacterial activity .

HY-116757

(±)-α-CMBHC	Cardiovascular Disease Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-α-CMBHC is a metabolite of α-Tocopherol .

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-152899

Selachyl alcohol	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Selachyl alcohol is an orally active antihypertensive agent. Selachyl alcohol has similar activities with antihypertensive neutral renomedullary lipid (ANRL). Selachyl alcohol is an alkylglycerol compound in shark liver oil mixture with properties that reduce lung metastasis. Selachyl alcohol can be used for cardiovascular disease research .

HY-138800

Spinosad	Structural Classification Natural Products Microorganisms Neurological Disease Classification of Application Fields Source classification Disease Research Fields Biological Pesticide Research Agricultural Research	nAChR
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .

HY-B0778

Milbemycin oxime	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Antibiotic Parasite
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-15311

Avermectin B1 4 Publications Verification Abamectin; Avermectin B1a-Avermectin B1b mixt.	Structural Classification Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Biological Pesticide Research Agricultural Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Inflammation/Immunology Disease Research Fields	Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .

HY-B1341

Norethynodrel Enidrel; SC 4642; NSC 15432	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
Norethynodrel (Enidre) is a 19-nortestosterone derivative to be used as a progestagen. Norethynodrel can be used for researching inhibition of ovulation . Norethynodrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N1651

2,3',4,6-Tetrahydroxybenzophenone	Structural Classification Gentiana lutea L. Source classification Gentianaceae Phenols Polyphenols Plants	Others
2,3',4,6-Tetrahydroxybenzophenone, a kind of benzophenone, is the immediate precursor of xanthones in higher plants .

HY-A0098

Tunicamycin Maximum Cited Publications 80 Publications Verification	Structural Classification Antifungal Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Antiviral Anticancer Inflammation/Immunology Disease Research Fields	Bacterial Fungal Influenza Virus Antibiotic
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .

HY-N9686

Caffeoyl-CoA	Natural Products Gramineae Source classification Secale cereale Plants	Others
Caffeoyl-CoAcould be isolated from leaf tissues of Gramineae with a K_m value of 1.45 μM .

HY-N3905

Fragransin A2 (+)-Fragransin A2	Structural Classification Knema tenuinervia W. J. de Wilde Source classification Phenols Polyphenols Myristicaceae Plants	Others
Fragransin A2 is a lignan that can be isolated from the stems of Knema furfuracea (Myristicaceae). Fragransin A2 shows anticancer activity .

HY-N9075

9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one	Structural Classification Monophenols Source classification Phenols Musaceae Plants Musa basjoo Sieb. et Zucc.	Glucosidase
9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one is a phytoalexin and mixed competitive α-glucosidase inhibitor of Bacillus stearothermophilus (IC₅₀: 3.86 mg/L) .

HY-122416

6,8-Diprenylnaringenin Lonchocarpol A; Senegalensin	Structural Classification Classification of Application Fields Erythrinasenegalensis DC. Source classification Metabolic Disease Plants Moraceae Flavonoids Leguminosae Humulus lupulus L. Flavonones Phenols Polyphenols Disease Research Fields Cancer	BCRP
6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and ³H-Methotrexate transport (IC₅₀=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin .

Cat. No.	Product Name	Chemical Structure

HY-132382S

β-Sitosterol-d7 (mixture of diasteromers)

β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].
HY-134670S

α-Hydroxy Metoprolol-d5 (Mixture of Diastereomers)

α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].
HY-132676S

Ramiprilat-d5 (Mixture of Diastereomers)

Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)**
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-132379S

*Hydroxy Pioglitazone-d5 (M-IV) (Mixture* of-diastereomers)**
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-132485S

N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers)

N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers) is the deuterium labeled N-Methyl Pantoprazole (Mixture of 1 and 3 isomers) .
HY-132637S

Chlorfenvinphos-d10(Mixture of cis-trans isomers)

Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-W018772S15

D-Ribose(mixture of isomers)-13C5

D-Ribose(mixture of isomers)- ¹³C₅ isomers)- ¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

HY-107327S

Carazolol-d7

Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7

Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-12057S1

Vemurafenib-d7
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

HY-Y0376S

DMPA-d7

DMPA-d₇ is the deuterium labeled DMPA[1].
HY-41700S3

D-Alanine-d7

D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-135328S

Norverapamil-d7
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

HY-B0679S

Lubiprostone-d7
Lubiprostone-d₇ (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

HY-50898S1

Lapatinib-d7 dihydrochloride
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-12296S

Navtemadlin-d7
Navtemadlin-d₇ is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

HY-13720AS

Pergolide-d7 mesylate
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-12785S1

Albendazole sulfoxide-d7
Albendazole sulfoxide-d₇ is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

HY-14268S1

Febuxostat-d7

Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

HY-B1674S4

(±)-Leucine-d7
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

HY-N0650S11

L-Serine-d7
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N7745S

Glucosylsphingosine-d7

Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-135853S

Molnupiravir-d7

Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

HY-14275S1

Verapamil-d7
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-101047S

D-erythro-Sphingosine-d7
D-erythro-Sphingosine-d₇ is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].

HY-B0763S2

Ibudilast-d7-1

Ibudilast-d₇-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].

HY-Y1772S

1-Iodo-4-methylbenzene-d7

1-Iodo-4-methylbenzene-d₇ is the deuterium labeled 1-Iodo-4-methylbenzene[1].

HY-14291S1

Vildagliptin-d7
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-B1178S2

(Rac)-Cotinine-d7

(Rac)-Cotinine-d₇ is deuterium labeled Cotinine.

HY-N2026S

Propylparaben-d7

Propylparaben-d₇ (Propyl parahydroxybenzoate-d₇)is the deuterium labeledPropylparaben(HY-N2026) . Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats .

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-41463S

4-(Butylamino)benzoic acid-d7

4-(Butylamino)benzoic acid-d₇ is the deuterium labeled 4-(Butylamino)benzoic acid[1].

HY-B0978S1

Diethyltoluamide-d7
Diethyltoluamide-d₇ is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].

HY-10003S

Alfacalcidol-d7
Alfacalcidol-d₇ is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis[1][2][3][4].

HY-111975S5

7'-Hydroxy ABA-d7

7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].
HY-120986S

(S)-Bromoenol lactone-d7

(S)-Bromoenol lactone-d₇ is the deuterium labeled (S)-Bromoenol lactone[1].
HY-B0648S1

Medroxyprogesterone-d7

Medroxyprogesterone-d₇ is deuterium labeled Medroxyprogesterone.

HY-18569S3

3-Indoleacetic acid-d7
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-B0389S

D-Glucose-13C6,d7

D-Glucose- ¹³C₆,d₇ is the deuterium and ¹³C labeled D-Glucose[1].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Species:	Human (130) Virus (1) Mouse (20) Rat (2) E.coli (3) Cynomolgus (1)
Tag:	SUMO (15) T7 (1) GST (23) Flag (3) GFP (3) His (121) Tag Free (18) Strep (4) Avi (3) Myc (5) MBP (1) Trx (2) Fc (5)
Source:	HEK293 (43) E. coli Cell-free (12) CHO (1) Sf9 insect cells (25) P. pastoris (3) E. coli (75)


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

β-Sitosterol-d<sub>7</sub> (Mixture of Diastereomers)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
Products